A goal of biology is to predict how mutations combine to alter phenotypes, fitness and disease. It is often assumed that mutations combine additively or with interactions that can be predicted. I will describe our work showing that this assumption is incorrect. Mutations combine differently at different expression levels. Sometimes predicting how mutations combine would be impossible even with perfect measurements of the mutational effects on a trait and the mechanistic understanding of the genetic system.

To further emphasize the importance of academic integrity, and carry forward the research spirit. Residential College is going to hold a lecture on Academic Integrity and Innovation on September 21, 2020. The relevant matters are hereby notified as follows:

Topic: Academic Integrity and Innovation

参会要求：请国际校区全体研究生新生参加，提前15分钟进场，携带校园卡签到，若有特殊情况请向辅导员请假。